Abstract: In view of increasing incidence of chronic renal failure in Sri Lanka and demand for transplantation, it is important to evaluate the outcome of current transplant programmes. This retrospective analytical study aimed at making a database of patients who underwent renal transplant under the Faculty of Medicine (Colombo) renal transplant programme during the two year period from 31st December 2004 to 31st December 2006. The emphasis was on post KT infections and complications of renal transplants. Statistical analysis was done using SPSS. There were a total of 73 (n=73) patients transplanted in the given time period, 46 (62.5 %) at National Hospital and 27 (37.5 %) at Western infirmary. Eighteen (25%) had died by February 2007. Forty three patients (58.3%) were interviewed and twelve patients could not be contacted. Of the interviewed, 28 (38.9%) were on Azathioprin, Prednisolone and Cyclosporin while 15 (20.8%) were on Prednisolone, Cyclosporine and Mycophenolate mofetil. In the sample, 4 patients had Cytomegalovirus (CMV) and 5 has had Tuberculosis (TB) post transplant. Out of all infections, the most commonly reported one was urinary tract infection. (11 cases) There was no significant benefit in protection against acute rejection in those who took induction therapy. Acute rejection was the most commonly encountered early complication with 9 cases (12.5 %) being reported. Of late complications most were due to immunosuppression. There was no statistically significant difference in surgical complications in government and private sector. Survival of patients also showed no significant difference depending on center of transplant.

chaturaka Rodrigo¹, Rikaz Sheriff², Senaka Rajapakse³, Rushika Lanerolle³, Rezvi Sheriff³

¹University medical unit, National Hospital of Sri Lanka, ²Western Infirmary, Colombo, Sri Lanka, ³Department of Clinical Medicine, Faculty of Medicine, University of Colombo

Keywords: Renal transplant , Post-transplant infections , induction therapy